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Recombinant Human GRO-alpha (CXCL1), His Tag
Recombinant Human GRO-alpha (CXCL1), His Tag
- 中文名称:
- Recombinant Human GRO-alpha (CXCL1), His Tag
- 英文名称:
- Recombinant Human GRO-alpha (CXCL1), His Tag
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38754
- 规格:
- 0.01 mg|0.05 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Liquid CXCL1 although stable at 10 degree C for 1 week, should be stored below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- Greater than 90.0% as determined by SDS-PAGE.
- 产品形式:
- CXCL1 in 20mM Tris-HCL pH-8 and 10% glycerol.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: CXCL1 Human Recombinant produced in E Coli is a single,non-glycosylated, polypeptide chain containing 94 amino acids (35-107) and having a molecular mass of 10.1 kDa. The CXCL1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-?). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.