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Recombinant Human Tumor Protein p53 Inducible Protein 3
Recombinant Human Tumor Protein p53 Inducible Protein 3
- 中文名称：
- Recombinant Human Tumor Protein p53 Inducible Protein 3
- 英文名称：
- Recombinant Human Tumor Protein p53 Inducible Protein 3
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38827
- 规格：
- 0.005 mg|0.025 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- TP53I3 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 90% as determined by SDS-PAGE.
- 产品形式：
- 1mg/ml solution containing 20mM Tris HCl pH-8, 0.1M NaCl & 10% glycerol.
Sterile filtered colorless solution.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: TP53I3 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 352 amino acids (1-332 a.a.) and having a molecular mass of 37.6 kDa. TP53I3 protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
Introduction: TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
