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Recombinant Human V-Myc Myelocytomatosis Viral Oncogene
Recombinant Human V-Myc Myelocytomatosis Viral Oncogene
- 中文名称：
- Recombinant Human V-Myc Myelocytomatosis Viral Oncogene
- 英文名称：
- Recombinant Human V-Myc Myelocytomatosis Viral Oncogene
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38885
- 规格：
- 0.002 mg|0.01 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- 请按照说明书指示
- 货期：
- 6-8周
- 纯度：
- Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
- 产品形式：
- Myc was lyophilized after extensive dialysis against PBS.
Sterile Filtered White lyophilized (freeze-dried) powder.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Myc Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 439 amino acids and having a molecular mass of 48.8kDa.The Myc is fused to a C-terminal poly-arginine tag and purified by proprietary chromatographic techniques.
Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
