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Recombinant Human Activating Transcription Factor-3
Recombinant Human Activating Transcription Factor-3
- 中文名称：
- Recombinant Human Activating Transcription Factor-3
- 英文名称：
- Recombinant Human Activating Transcription Factor-3
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38917
- 规格：
- 0.005 mg|0.02 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store at 4 degree C if entire vial will be used in 2-4 weeks. Store frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 90.0% as determined by Analysis by SDS-PAGE.
- 产品形式：
- ATF3 protein (1mg/ml) is supplied in 20mM Tris-HCL, pH-8, 2M Urea and 20% Glycerol.
ATF3 is supplied as a sterile filtered clear solution.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: ATF3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 181 amino acids (1-181) and having a molecular mass of 20.6 kDa.The ATF3 is purified by proprietary chromatographic techniques.
Introduction: ATF3 belongs to the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in numerous viral and cellular promoters. Multiple transcript variants encoding two different isoforms are known for this gene. The longer isoform represses transcription from promoters with ATF binding elements instead of activating it. The shorter isoform (deltaZip2) which stimulates transcription by sequestering inhibitory co-factors away from the promoter has no leucine zipper protein-dimerization motif and does not bind to DNA.
