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Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 1
Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 1
- 中文名称：
- Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 1
- 英文名称：
- Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 1
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38965
- 规格：
- 0.005 mg|0.02 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store at 4°C if entire vial will be used with 2-4 weeks.
Store, frozen at - 20°C for longer periods of time.
For longer storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 90.0% as determined by SDS-PAGE.
- 产品形式：
- The MAPRE1 solution (0.5 mg/ml) 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: MAPRE1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 288 amino acids (1-268 a.a.) and having a molecular mass of 32.2kDa. The MAPRE1 is purified by proprietary chromatographic techniques.
Introduction: MAPRE1 (EB1) is a member of the intermediate/early gene family. MAPRE1 was first identified by its binding to the APC protein, which is often mutated in familial and sporadic, forms of colorectal cancer. MAPRE1 localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, MAPRE1 is associated with the centrosomes and spindle microtubules. MAPRE1 is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes.
