-
Recombinant Human Branched Chain keto Acid Dehydrogenase E1, Alpha
Recombinant Human Branched Chain keto Acid Dehydrogenase E1, Alpha
- 中文名称：
- Recombinant Human Branched Chain keto Acid Dehydrogenase E1, Alpha
- 英文名称：
- Recombinant Human Branched Chain keto Acid Dehydrogenase E1, Alpha
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38996
- 规格：
- 0.001 mg|0.005 mg|0.05 mg|2x0.05 mg|3x0.05 mg
- 保存建议：
- Store at 4°C if entire vial will be used within 2-4 weeks
Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 80.0% as determined by SDS-PAGE.
- 产品形式：
- The BCKDHA solution (0.25 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 30% glycerol and 0.2M NaCl.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: BCKDHA Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 421 amino acids (46-445 a.a.) and having a molecular mass of 47.8kDa. The BCKDHA is purified by proprietary chromatographic techniques.
Introduction: Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain (BCKDHA) is a member of the BCKDHA family. The BCKD (branched-chain alpha-keto acid dehydrogenase) complex is an inner mitochondrial enzyme complex which catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. This complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). Mutations in the BCKDHA gene result in maple syrup urine disease, type IA.
