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Recombinant Human BUB3
Recombinant Human BUB3
- 中文名称:
- Recombinant Human BUB3
- 英文名称:
- Recombinant Human BUB3
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA39052
- 规格:
- 0.005 mg|0.02 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 纯度:
- Greater than 85.0% as determined by SDS-PAGE.
- 产品形式:
- BUB3 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile Filtered clear solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: BUB3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 351 amino acids (1-328 a.a.) and having a molecular mass of 39.5kDa.BUB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Mitotic checkpoint protein BUB3,(BUB3), is a saved component of the mitotic spindle assembly complex (MCC). The encoded protein has 4 WD repeat domains and has a similar sequence as the yeast BUB3 protein. BUB3 is vital for the kinetochore localization of BUB1 and BUBR1. BUB3 participates in the central spindle checkpoint pathway that operates during early embryogenesis. Furthermore BUB3 has a part in regulating the establishment of correct kinetochore-microtubule attachments.