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Recombinant Streptococcus Pyogenes Streptolysin-O
Recombinant Streptococcus Pyogenes Streptolysin-O
- 中文名称：
- Recombinant Streptococcus Pyogenes Streptolysin-O
- 英文名称：
- Recombinant Streptococcus Pyogenes Streptolysin-O
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA39153
- 规格：
- 0.02 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Lyophilized Streptolysin-O although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptolysin-O should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
- 产品形式：
- Streptolysin-O protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant Streptococcus Pyogenes Streptolysin-O produced in E Coli is a single, non-glycosylated, polypeptide chain containing 538 amino acids and having a molecular mass of 60.1kDa. The Streptolysin-O is purified by proprietary chromatographic techniques.
Streptolysin-O is a sulfhydryl-activated toxin which causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the Streptolysin-O protein undergoes a major conformation change, leading to its insertion in the host membrane and creation of an oligomeric pore complex. Cholesterol may be needed for binding to host membranes, membrane insertion and pore formation. Streptolysin-O can be reversibly inactivated by oxidation.
