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Recombinant SARS-CoV-2 (2019-nCoV) PL-Pro
Recombinant SARS-CoV-2 (2019-nCoV) PL-Pro
- 中文名称：
- Recombinant SARS-CoV-2 (2019-nCoV) PL-Pro
- 英文名称：
- Recombinant SARS-CoV-2 (2019-nCoV) PL-Pro
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA41016
- 规格：
- INQUIRE
- 保存建议：
- Store at 2 to 8°C for one week.
Store at -20 to -80°C for twelve months from the date of receipt.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Shipping: Blue Ice
- 货期：
- 6-8周
- 纯度：
- >90% as determined by SDS-PAGE
- 产品形式：
- Supplied as lyophilized from PBS, pH7.5, 4M urea
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant SARS-CoV-2 PL-Pro is produced by E.coli expression system and the target gene encoding Glu1564-IIe1877 is expressed with N-His Tag
Background: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
