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Malondialdehyde (MDA) Modified Low Density Lipoprotein (LDL)
Malondialdehyde (MDA) Modified Low Density Lipoprotein (LDL)
- 中文名称：
- Malondialdehyde (MDA) Modified Low Density Lipoprotein (LDL)
- 英文名称：
- Malondialdehyde (MDA) Modified Low Density Lipoprotein (LDL)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA44575
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Store at -20°C; aliquot to avoid freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- 98% by SDS-PAGE
- 产品形式：
- 100 ug at 1.0 mg/mL in PBS, pH 7.4, containing 1 mM EDTA, 0.02% NaN3 and 50% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
• Provided at a concentration of 1.0 mg/mL
Lipid peroxidation is a well-defined mechanism of cellular damage in animals and plants. Lipid peroxides are unstable indicators of oxidative stress in cells that decompose to form more complex and reactive compounds such as Malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), natural bi-products of lipid peroxidation. Oxidative modification of lipids can be induced in vitro by a wide array of pro-oxidant agents and occurs in vivo during aging and in certain disease conditions. Measuring the end products of lipid peroxidation is one of the most widely accepted assays for oxidative damage. These aldehydic secondary products of lipid peroxidation are generally accepted markers of oxidative stress.
Both MDA and HNE have been shown to be capable of binding to proteins and forming stable adducts, also termed advanced lipid peroxidation end products. These modifications of proteins by MDA or HNE can cause both structural and functional changes of oxidized proteins.
