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Recombinant human CSF1R protein with C-terminal 6xHis tag
Recombinant human CSF1R protein with C-terminal 6xHis tag
- 中文名称:
- Recombinant human CSF1R protein with C-terminal 6xHis tag
- 英文名称:
- Recombinant human CSF1R protein with C-terminal 6xHis tag
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47232
- 规格:
- 0.01 mg|0.05 mg|0.1 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
- 货期:
- 6-8周
- 纯度:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- 产品形式:
- Lyophilized from sterile PBS, pH 7.4. Normally 5%-59% trehalose is added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.