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Human CD160 Protein, hFc Tag
Human CD160 Protein, hFc Tag
- 中文名称:
- Human CD160 Protein, hFc Tag
- 英文名称:
- Human CD160 Protein, hFc Tag
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47339
- 规格:
- 0.01 mg|0.05 mg|0.1 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
- 货期:
- 6-8周
- 纯度:
- >95%. Affinity purification
- 产品形式:
- Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]