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Human IL4RA Protein, hFc Tag
Human IL4RA Protein, hFc Tag
- 中文名称:
- Human IL4RA Protein, hFc Tag
- 英文名称:
- Human IL4RA Protein, hFc Tag
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47365
- 规格:
- 0.01 mg|0.05 mg|0.1 mg|2x0.1 mg|3x0.1 mg
- 保存建议:
- Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
- 货期:
- 6-8周
- 纯度:
- Affinity purification
- 产品形式:
- Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.