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Recombinant human Epiregulin protein
Recombinant human Epiregulin protein
- 中文名称:
- Recombinant human Epiregulin protein
- 英文名称:
- Recombinant human Epiregulin protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48415
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议:
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 90% by SDS-PAGE
- 产品形式:
- Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Epiregulin is a member of the epidermal growth factor family. It is expressed primarily in the placenta and macrophages and high level expression has also been detected in various carcinomas. This protein contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation. Epiregulin is growth factors involved in cancer development. Deregulated epiregulin activity appears to contribute to the progression of a number of different malignancies, including cancers of the bladder, stomach, colon, breast, lung, head and neck, and liver. It inhibit the growth of several epithelial tumor cells and stimulated the growth of fibroblasts and various other types of cells. In addition, it has been implicated in the implantation process during pregnancy. Recombinant human Epiregulin, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.