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Hif-1a, 530-826aa, Human, E Coli
Hif-1a, 530-826aa, Human, E Coli
- 中文名称：
- Hif-1a, 530-826aa, Human, E Coli
- 英文名称：
- Hif-1a, 530-826aa, Human, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48450
- 规格：
- 0.02 mg|0.1 mg|0.5 mg|5x0.02 mg|5x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl pH7.5, 1mMDTT
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1beta subunit and one of three subunits (Hif-1alpha, Hif-2 or Hif-3). The activation of Hif-1 is closely associated with a variety of tumors and oncogenic pathways. Hif-1alpha consists of DNA binding domain (DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains (TAD), an oxygen-dependent degradation (ODD) domain, and inhibitory domains. Hif-1 alpha (530-826 residues) contains two TAD and inhibitory domain. Recombinant Hif-1 alpha (530-826 residues) was expressed in E Coli and purified by using conventional chromatography techniques.
