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HtrA2/Omi, 134-458aa, Human, His tag, E Coli
HtrA2/Omi, 134-458aa, Human, His tag, E Coli
- 中文名称:
- HtrA2/Omi, 134-458aa, Human, His tag, E Coli
- 英文名称:
- HtrA2/Omi, 134-458aa, Human, His tag, E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48468
- 规格:
- 0.02 mg|0.1 mg|0.5 mg|5x0.02 mg|5x0.1 mg
- 保存建议:
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE
- 产品形式:
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0), 50 mM NaCl, 1 mM DTT, 20% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
HtrA2/Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Mature form of HtrA2/Omi (residues 134-458) was overexpressed in E Coli, and purified by conventional column chromatography techniques.