-
Elongin B, 1-118aa, Human, E Coli
Elongin B, 1-118aa, Human, E Coli
- 中文名称：
- Elongin B, 1-118aa, Human, E Coli
- 英文名称：
- Elongin B, 1-118aa, Human, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48501
- 规格：
- 0.02 mg|0.1 mg|0.5 mg|5x0.02 mg|5x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1mMDTT, 0.1mM PMSF, 20% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Elongin B, also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant TCEB2 was expressed as insoluble protein aggregate in E Coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
