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PTEN, 1-403aa, Human, His tag, E Coli
PTEN, 1-403aa, Human, His tag, E Coli
- 中文名称:
- PTEN, 1-403aa, Human, His tag, E Coli
- 英文名称:
- PTEN, 1-403aa, Human, His tag, E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48549
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议:
- Can be stored at 2°C to 8°C for one week.
For long term storage, aliquot and store at -20°C or -80°C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 85% by SDS-PAGE
- 产品形式:
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1mM EDTA, 2mM DTT, 100mM NaCl, and 20% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
PTEN, also known as phosphatase and tensin homolog, is a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein acts as both a dual-specificity protein phosphatase and a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate. PTEN negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. Recombinant PTEN protein was expressed in E Coli and purified by using conventional chromatography techniques.