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FEN1, 1-380aa, Human, E Coli
FEN1, 1-380aa, Human, E Coli
- 中文名称:
- FEN1, 1-380aa, Human, E Coli
- 英文名称:
- FEN1, 1-380aa, Human, E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48575
- 规格:
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议:
- Can be stored at +2°C to +8°C for one week
For long term storage, aliquot and store at -20°C or -80°C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 90% by SDS-PAGE
- 产品形式:
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E Coli and purified by using conventional chromatography techniques.