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14-3-3 sigma, 1-248aa, Human, E Coli
14-3-3 sigma, 1-248aa, Human, E Coli
- 中文名称：
- 14-3-3 sigma, 1-248aa, Human, E Coli
- 英文名称：
- 14-3-3 sigma, 1-248aa, Human, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48633
- 规格：
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议：
- For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 50mM NaCl, 10% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
14-3-3 sigma,also known as Stratifin (SFN), belong to the 14-3-3 family. The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 sigma was identified as an epithelial cell marker and appeared to function as a tumor suppressor whose expression can be down regulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis. Recombinant human 14-3-3 sigma was expressed in E Coli and purified by using conventional chromatography techniques.
