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IMPDH1, 1-514aa, Human, His tag, E Coli
IMPDH1, 1-514aa, Human, His tag, E Coli
- 中文名称：
- IMPDH1, 1-514aa, Human, His tag, E Coli
- 英文名称：
- IMPDH1, 1-514aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48641
- 规格：
- 0.01 mg|0.05 mg|5x0.01 mg|0.25 mg|5x0.05 mg
- 保存建议：
- Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 20% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Inosine-5'-monophosphate dehydrogenase 1, also known as IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). Also, IMPDH1 is a ubiquitously expressed enzyme, functioning as a homotetramer, which catalyzed the rate-limiting step in de novo synthesis of guanine nucleotides. As such, it plays an important role in cyclic nucleoside metabolism within photoreceptors. Defects in the IMPDH1 gene are a cause of retinitis pigmentosa type 10. Recombinant human IMPDH1, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
