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APP, 18-289aa, Human, His tag, E Coli
APP, 18-289aa, Human, His tag, E Coli
- 中文名称：
- APP, 18-289aa, Human, His tag, E Coli
- 英文名称：
- APP, 18-289aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48718
- 规格：
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议：
- Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 85% by SDS-PAGE
- 产品形式：
- Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
APP, also known as amyloid beta A4 protein, functions as a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Recombinant human APP protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
