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NEu1, 48-415aa, Human, His tag, E Coli
NEu1, 48-415aa, Human, His tag, E Coli
- 中文名称:
- NEu1, 48-415aa, Human, His tag, E Coli
- 英文名称:
- NEu1, 48-415aa, Human, His tag, E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48731
- 规格:
- 0.02 mg|0.1 mg|2x0.1 mg|5x0.02 mg|3x0.1 mg
- 保存建议:
- Can be stored at 2-8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 85% by SDS-PAGE
- 产品形式:
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
NEu1 is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red -myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. Recombinant human NEu1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.