-
uPK3A, 19-207aa, Human, His tag, E Coli
uPK3A, 19-207aa, Human, His tag, E Coli
- 中文名称：
- uPK3A, 19-207aa, Human, His tag, E Coli
- 英文名称：
- uPK3A, 19-207aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48745
- 规格：
- 0.01 mg|0.05 mg|5x0.01 mg|0.25 mg|5x0.05 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
uPK3A belongs to the uroplakin-3 family. uroplakins (uP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (uPII, uPIIIa, and uPIIIb) or four times (uPIa and uPIb; both belonging to the 'tetraspanin' family). All have large luminal/extracellular domains, but only uPIIIa and uPIIIb have significant cytoplasmic portions in their C-termini. uPK3A is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Mutations in this gene may be associated with renal adysplasia Recombinant human uPK3A protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
