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MAPK14, 1-360aa, Human, His tag, E Coli
MAPK14, 1-360aa, Human, His tag, E Coli
- 中文名称：
- MAPK14, 1-360aa, Human, His tag, E Coli
- 英文名称：
- MAPK14, 1-360aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48775
- 规格：
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
MAPK14 (Mitogen-activated protein kinase 14) is a member of the MAP kinase family. MAPK14 is most closely related to p38 MAP kinases (MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Recombinant human MAPK14 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
