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uBA5, 1-404aa, human, His tag, E Coli
uBA5, 1-404aa, human, His tag, E Coli
- 中文名称:
- uBA5, 1-404aa, human, His tag, E Coli
- 英文名称:
- uBA5, 1-404aa, human, His tag, E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48788
- 规格:
- 0.01 mg|0.05 mg|5x0.01 mg|0.25 mg|5x0.05 mg
- 保存建议:
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 90% by SDS-PAGE
- 产品形式:
- Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50mM NaCl
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
uBA5 (ubiquitin-like modifier activating enzyme 5) belongs to the ubiquitin-activating E1 family and uBA5 subfamily. ubiquitin and ubiquitin-like proteins are known to be covalently conjugated to a variety of cellular substrates via a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) plays a key role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. uBA5 had been proved to activate an ubiquitin-like protein, ubiquitin-fold modifier 1 (ufm1), by forming a high-energy thioester bond. It localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SuMO2. Recombinant human uBA5 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.