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CADM1, 45-374aa, Human, His tag, E Coli
CADM1, 45-374aa, Human, His tag, E Coli
- 中文名称：
- CADM1, 45-374aa, Human, His tag, E Coli
- 英文名称：
- CADM1, 45-374aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48903
- 规格：
- 0.004 mg|0.02 mg|5x0.004 mg|0.1 mg|5x0.02 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 85% by SDS-PAGE
- 产品形式：
- Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol, 1mM DTT
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
CADM1 mediates homophilic cell-cell adhesion in a Ca2+-independent manner and also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. This protein acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Recombinant human CADM1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
