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PAX8, 1-287aa, Human, His tag, E Coli
PAX8, 1-287aa, Human, His tag, E Coli
- 中文名称：
- PAX8, 1-287aa, Human, His tag, E Coli
- 英文名称：
- PAX8, 1-287aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48912
- 规格：
- 0.01 mg|0.05 mg|5x0.01 mg|0.25 mg|5x0.05 mg
- 保存建议：
- Can be stored at 2-8°C for 1 week. .
For long term storage, aliquot and store at -20°C to -80°C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. In phosphate buffer saline (pH 7.4) containing 20% glycerol, 1mM DTT
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Paired box protein Pax-8 isoform PAX8E, also known as PAX8, is expressed in the developing and adult thyroid, the developing secretory system and at lower levels, in the adult kidney. PAX8complexes with TTF-1 and TTF-2 to induce thyroid follicular cell differentiation and thyroid hormone biosynthesis by regulating the expression of sodium iodide symporter (NIS), thyroid peroxidase (TPO), thyroglobulin (TG) and the thyrotropin receptor (TSHR). Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2). Recombinant human PAX8 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
