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Recombinant Human Interleukin-11
Recombinant Human Interleukin-11
- 中文名称：
- Recombinant Human Interleukin-11
- 英文名称：
- Recombinant Human Interleukin-11
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA50427
- 规格：
- 0.01 mg|2x0.01 mg|3x0.01 mg|4x0.01 mg|5x0.01 mg
- 保存建议：
- Prior to reconstitution store at -70 degree C. Following reconstitution store at -80 degree C.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- 货期：
- 6-8周
- 纯度：
- Recombinant protein expressed in E Coli and purified by ion exchange chromatography
>=90 % determined by coomassie blue staining of a reducing SDS-PAGE gel
- 产品形式：
- 50 mM Tris-HCl, pH8.0, 0.15 M NaCl
1.0% Trehalose
0.05% Tween80
Purified recombinant protein - lyophilized
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant Human interleukin-11
Interleukin-11 (IL-11), also known as AGIF belongs to the IL-6 family of cytokines, and plays a protective role in acute inflammatory settings (Traber et al. 2019). IL-11 has both pro- and anti-inflammatory functions through activation of signaling cascades (Lokau et al. 2017). IL-11 is largely absent in the body fluids of healthy people, but is upregulated in a series of diseases. IL-11 can be expressed in fibroblasts, and its inhibition has been suggested as a treatment for fibrotic disease (Schafer et al. 2017), including fibrotic cardiovascular diseases (Ye et al. 2019). A role of IL-11 has also been identified in development of inflammation-associated cancers, and its inhibition may be a therapeutic goal (Putoczki et al. 2013).
This recombinant Human interleukin-11 can be used to create a standard curve in a sandwich ELISA with purified Mouse anti Human interleukin-11 antibody, clone D08-4C12 as a capture antibody and biotinylated Mouse anti Human interleukin-11 antibody, clone C16-4B8 as the detection antibody.
