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Recombinant Human Procalcitonin (PCT) Protein
Recombinant Human Procalcitonin (PCT) Protein
- 中文名称:
- Recombinant Human Procalcitonin (PCT) Protein
- 英文名称:
- Recombinant Human Procalcitonin (PCT) Protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA55763
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Storage: Store it under sterile conditions at -20°C to -80°C upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.
Avoid repeated freeze-thaw cycles.
Stability: The recombinant protein is stable for up to 12 months from date of receipt at -80°C.
- 货期:
- 6-8周
- 纯度:
- > 90 % as determined by SDS-PAGE.
- 产品形式:
- The purified protein was Lyophilized from sterile PBS (58 mM Na2HPO4, 17 mM Na2HPO4, 68 mM NaCl, pH 7.0), 5 % trehalose and 5 % mannitol are added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.