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Recombinant Human Angiopoietin 2 (ANG2)
Recombinant Human Angiopoietin 2 (ANG2)
- 中文名称:
- Recombinant Human Angiopoietin 2 (ANG2)
- 英文名称:
- Recombinant Human Angiopoietin 2 (ANG2)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA55770
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Storage:
Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.
**Avoid repeated freeze-thaw cycles.**
Stability:
The recombinant protein is stable for up to 12 months from date of receipt at -80°C.
- 货期:
- 6-8周
- 纯度:
- > 90 % as determined by SDS-PAGE.
- 产品形式:
- 10 mM Tris-HCl, 1 mM EDTA, pH 8.0, with 20% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Angiopoietin-2 (Ang-2) is a secreted glycoprotein that plays a complex role in vascular development. Ang-2 contains an N-terminal coiled-coildomain, 58-254 amino acids (aa) and a C-terminal fibrinogen-like domain, 281-467 aa, that is also found in other proteins including fibrinogen, tenascin, and ficolin. Located at the N-terminus are stretches of hydrophobic residues typical of secretory signal sequences. While Ang-2 is widely expressed in the mouse embryo, it is restricted postnatally to pro-angiogenic regions including the placenta, ovaries, and uterus. Ang-2 has been implicated in cancer development due to its role in angiogenesis. Ang-2-mediated destabilization of mature vessel structures accompanied by the presence of VEGF, may contribute to the angiogenesis associated with tumor tissues.