
-
Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) Protein
Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) Protein
- 中文名称:
- Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) Protein
- 英文名称:
- Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) Protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA55977
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Store it under sterile conditions at -20°C upon receiving. Recommend to aliquot
the protein into smaller quantities for optimal storage.
**Avoid repeated freeze-thaw cycles.**
Stability: The recombinant protein is stable for up to 12 months from date of receipt at -80°C.
- 货期:
- 6-8周
- 纯度:
- > 90 % as determined by SDS-PAGE.
- 产品形式:
- In 1M PBS, pH 7.4-7.5, with 5% trehalose and 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. The ASGR1 gene encodes a glycoprotein that forms the asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. Partially deglycosylated plasma glycoproteins are efficiently and specifically removed from the circulation via this receptor-ligand complex. Many functional studies describing the kinetics of ligand-binding, internalization, and recycling of such receptors have been performed on the human hepatoma cell line HepG2.