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Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
- 中文名称：
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
- 英文名称：
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58754
- 规格：
- 0.01 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- 请按照说明书指示
- 货期：
- 6-8周
- 纯度：
- >95% by SDS-PAGE
- 产品形式：
- Liquid
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+-sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus. Recombinant mGPD comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature mGPD protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
