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Pregnancy Associated Plasma Protein-1 (PAPP-1A)
Pregnancy Associated Plasma Protein-1 (PAPP-1A)
- 中文名称：
- Pregnancy Associated Plasma Protein-1 (PAPP-1A)
- 英文名称：
- Pregnancy Associated Plasma Protein-1 (PAPP-1A)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA58762
- 规格：
- 0.01 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- 请按照说明书指示
- 货期：
- 6-8周
- 纯度：
- >95% by SDS-PAGE
- 产品形式：
- Liquid
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems. Recent studies have shown that levels are elevated in patients with unstable angina or acute myocardial infarction. PAPP-A is also produced in high concentrations during pregnancy and is released into the maternal circulation. Low levels of PAPP-A have been linked with a number of foetal chromosomal abnormalities, as well as pre-eclampsia and stillbirth. Recombinant PAPP-A comprises a 191 amino acid fragment (81-271) corresponding to the PAPP-A Jelly-Roll domain fragment and is expressed in E Coli with an aminoterminal hexahistidine tag. This product is not intended for therapeutic use.
