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S100BB Protein (Active)
S100BB Protein (Active)
- 中文名称：
- S100BB Protein (Active)
- 英文名称：
- S100BB Protein (Active)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59083
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Ship at 4 degree C.
Upon receipt, aliquot and store at -20 degree C or -80 degree C for long term.
Avoid repeated freeze and thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >95% by SDS-PAGE
- 产品形式：
- Liquid ; Each vial contains Tris-HCl (pH7.4 ± 0.2) with 0.1% NaN3.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
S100B (S100 calcium binding protein B) is a glial-derived protein that is a well-established biomarker for severity of neurological injury and prognosis for recovery. It functions as a neurotrophic factor and neuronal survival protein during development of the central nervous system. S100B is glial-specific and is expressed at high levels in brain primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells. The increased S100B in the brain can be detrimental and may augment pathogenic responses to injury by accelerating neuroinflammatory processes. Chromosomal rearrangements and altred expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. And the regulation of S100B by melittin has potential for the treatment of epilepsy.
