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S100A1B Protein (Active)
S100A1B Protein (Active)
- 中文名称:
- S100A1B Protein (Active)
- 英文名称:
- S100A1B Protein (Active)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59089
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- Ships on blue ice. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >95% by SDS-PAGE
- 产品形式:
- Liquid; Contains Tris-HCl (pH7.4 ± 0.2) with 0.1% NaN3.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Recombinant full length human S100A1B protein with molecular weight 22 kDa.
Background: S100 proteins, such as S100A1 (S100 calcium-binding protein A1), are small, acidic Ca(2+)-binding proteins that transduce Ca(2+) signals via interaction with intracellular target proteins. The protein encoded by this gene is a member of the S100 family of proteins containing 4 EF-hand calcium-binding motifs in its dimerized form. S100A1 is preferentially expressed in myocardial tissue and has been found to colocalize with the sarcoplasmic reticulum (SR) and the contractile filaments in cardiac tissue. Its overexpression enhances cardiac contractile performance and establish the concept of S100A1 as a regulator of myocardial contractility. S100A1 thus improves cardiac contractile performance bothby regulating SR Ca(2+) handling and myofibrillar Ca(2+) responsiveness.