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Procalcitonin, PCT
Procalcitonin, PCT
- 中文名称：
- Procalcitonin, PCT
- 英文名称：
- Procalcitonin, PCT
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59115
- 规格：
- 0.01 mg|2x0.01 mg|3x0.01 mg|5x0.01 mg|4x0.01 mg
- 保存建议：
- Shipping: Blue ice.
Upon receipt, aliquot and store at -20°C or -80°C for long term.
Avoid repeated freeze and thaw cycles
- 货期：
- 6-8周
- 纯度：
- >95% by SDS-PAGE
- 产品形式：
- Lyophilized from 0.01 M PBS (pH7.4) with 2% BSA and 0.03% Proclin 300.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human PCT protein with 6×His tag at N-terminal
Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It iscomposed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. The level of procalcitonin in the blood stream of healthy individuals is below the limit of detection (10 pg/mL) of clinical assays. Itslevel rises in a response to a proinflammatory stimulus, especially of bacterial origin. Measurement of PCT concentrations during multiple organ dysfunction syndrome provides more information about the severity and the course of the disease than that of CRP. It can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha.
