-
Recombinant BRD9 (130-259) protein, GST-Tag
Recombinant BRD9 (130-259) protein, GST-Tag
- 中文名称：
- Recombinant BRD9 (130-259) protein, GST-Tag
- 英文名称：
- Recombinant BRD9 (130-259) protein, GST-Tag
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA59715
- 规格：
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期：
- 6-8周
- 纯度：
- The recombinant protein is >95% pure by SDS-PAGE.
- 产品形式：
- Recombinant BRD9 (130-259), GST-Tag was expressed in E Coli cells and is supplied in 25mM Tris pH7.4, 150mM NaCl, 5% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Short Description: The peptide corresponding to amino acids 130-259 that contains the bromodomain sequences of BRD9 (accession number NM_023924.4) was expressed in E Coli and contains an N-terminal GST-Tag with an observed molecular weight of 41 kDa. The recombinant protein is >=95% pure by SDS-PAGE. Recombinant BRD9 (130-259) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
Background: BRD9 (Bromodomain-containing protein 9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.
