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Recombinant FTO protein
Recombinant FTO protein
- 中文名称:
- Recombinant FTO protein
- 英文名称:
- Recombinant FTO protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA59756
- 规格:
- 0.02 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant FTO protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl,10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Short Description: Recombinant FTO protein was expressed in a baculovirus expression system as the full-length protein (accession number XP_011521615.1) with an N-terminal DYKDDDDK-Tag. The molecular weight of FTO is 60.4 kDa. It is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. It can also be used for analysis of DNA repair, RNA repair, metabolism, energy and body fat homeostasis.
Background: FTO (Alpha-Ketoglutarate Dependent Dioxygenase, also known as GDFD, ALKBH9, BMIQ14) is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily. FTO specifically demethylates m6A RNA. FTO plays an important role in the regulation of the global metabolic rate, energy expenditure and energy homeostasis. It is involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells.