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Recombinant SUV420H2 protein
Recombinant SUV420H2 protein
- 中文名称:
- Recombinant SUV420H2 protein
- 英文名称:
- Recombinant SUV420H2 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60105
- 规格:
- 0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg|5x0.02 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant SUV420H2 protein is supplied at a concentration of 0.3ug/ul in 25mM Tris pH8.0, 300mM NaCl, 5% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Short Description: Recombinant SUV420H2 protein was expressed in E Coli as full-length protein (accession number NP_116090.2) and contains an N-terminal GST-Tag with an observed molecular weight of 78.4 kDa. It is suitable for use in histone methyltransferase (HMT) assays.
Background: SUV420H2 (Suppressor Of Variegation 4-20 Homolog 2, also known as KMT5C) is a histone methyltransferase that specifically trimethylates nucleosomal histone H4 on lysine 20 (H4K20). H4K20me3 is a histone marker that represents epigenetic transcriptional repression. SUV420H2 mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H2 is targeted to histone H3 via its interaction with RB1 family proteins.