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Recombinant ALKBH2 protein
Recombinant ALKBH2 protein
- 中文名称:
- Recombinant ALKBH2 protein
- 英文名称:
- Recombinant ALKBH2 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60148
- 规格:
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant ALKBH2 protein is supplied in 25mM Tris pH8.0, 300mM NaCl, 20% glycerol, 0.5mM TCEP.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Short Description: Full-length ALKBH2 protein (accession number NP_001001655.1) was expressed in E Coli with an N-terminal 6xHis-tag. The molecular weight of ALKBH2 is 33.1 kDa. Recombinant ALKBH2 protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: ALKBH2 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH2 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.