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Recombinant BRDT (21-137) protein, GST-Tag
Recombinant BRDT (21-137) protein, GST-Tag
- 中文名称:
- Recombinant BRDT (21-137) protein, GST-Tag
- 英文名称:
- Recombinant BRDT (21-137) protein, GST-Tag
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60165
- 规格:
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant BRDT (21-137) protein, GST-Tag is supplied in 25mM Tris-HCl pH8.0, 300mM NaCl, 10% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Short Description: Recombinant BRDT (21-137) protein, GST-Tag includes amino acids 21-137 (Bromodomain) of human BRDT protein (accession number NP_001229735.2); it was expressed in E Coli and contains an N-terminal GST-Tag with a molecular weight of 40.2 kDa. This protein is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
Background: BRDT is similar to the RING3 protein family. It possesses two bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. It shows binding specificity for acetylated H2BK12/15, H3K9/14/18/23, H4K12, H4K5/8, H4K8/12, H4K12/16, H4K5/12, H4K5/8/12/16 and H4K5/8/12/16.