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Recombinant MLLT3/AF9 (1-138) protein, His/DYKDDDDK Tag
Recombinant MLLT3/AF9 (1-138) protein, His/DYKDDDDK Tag
- 中文名称：
- Recombinant MLLT3/AF9 (1-138) protein, His/DYKDDDDK Tag
- 英文名称：
- Recombinant MLLT3/AF9 (1-138) protein, His/DYKDDDDK Tag
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60171
- 规格：
- 0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg|5x0.02 mg
- 保存建议：
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant MLLT3/AF9 (1-138) protein, His/DYKDDDDK-Tag is supplied in 25mM Tris-HCl pH7.4, 500mM NaCl, 10% glycerol, 1mM Na-EDTA and 0.5mM TCEP.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Short Description: Recombinant human MLLT3/AF9 (1-138) protein, His/DYKDDDDK-Tag includes amino acids 1-138 (accession number NP_004520.2) was expressed in E Coli with an N-terminal 6xHis-tag and a C-terminal DYKDDDDK-Tag. The molecular weight of the protein is 20.8 kDa. It is suitable for use in in binding assays, inhibitor screening, and selectivity profiling.
Background: MLLT3 (Myeloid/Lymphoid Or Mixed-Lineage Leukemia; translocated To, 3), also known as AF9 or-YEATS3, is a component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. It specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. In the SEC complex, MLLT3 is required to recruit the complex to crotonylated histones.
