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Recombinant SETD6 protein
Recombinant SETD6 protein
- 中文名称：
- Recombinant SETD6 protein
- 英文名称：
- Recombinant SETD6 protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60205
- 规格：
- 0.02 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant SETD6 protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Short Description: Full-length human SETD6 protein (accession number NP_079136.2) was expressed in a baculovirus expression system and contains an N-terminal DYKDDDDK tag. The molecular weight of SETD6 is 52.1 kDa. Recombinant SETD6 protein is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: SETD6 (SET Domain Containing 6, Protein Lysine Methyltransferase) is a member of SETD family, which has methyltransferase activity. This protein was reported to monomethylate 'Lys-8' of histone H2AZ, which is involved in nuclear receptor-dependent transcription. SETD6 was also reported to monomethylates 'Lys-310' of the RELA subunit of NF kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. It may interact with several endogenous proteins which are involved in nuclear hormone receptor signaling. However, the real substrates remain unknown for a very long time.
