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Recombinant MBD2-MBD protein
Recombinant MBD2-MBD protein
- 中文名称:
- Recombinant MBD2-MBD protein
- 英文名称:
- Recombinant MBD2-MBD protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60371
- 规格:
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant MBD2-MBD protein is supplied in 25 mM Tris 8.0, 300mM NaCl, 20% glycerol, 0.5 mM TCEP.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
MBD2 (Methyl-CpG-binding domain protein 2)is a transcriptional repressor that Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Also binds hemimethylated DNA as well and recruits histone deacetylases and DNA methyltransferases to chromatin. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.