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Recombinant UBE2D2 protein
Recombinant UBE2D2 protein
- 中文名称:
- Recombinant UBE2D2 protein
- 英文名称:
- Recombinant UBE2D2 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60393
- 规格:
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 货期:
- 6-8周
- 纯度:
- >=70% by SDS-PAGE.
- 产品形式:
- Recombinant UBE2D2 protein is supplied in 25 mM Tris 7.4, 300mM NaCl, 20% glycerol, 0.5 mM TCEP.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
UBE2D2 (Ubiquitin-conjugating enzyme E2 D2) also known as E2(17) KB2, PUBC1, UBC4, UBC4/5, UBCH4 and UBCH5B. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family which is required for post replicative DNA damage repair and plays an important role in various cellular processes. UBE2D2 can accept ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6 AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2 mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection.