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Bovine prolactin soluble receptor
Bovine prolactin soluble receptor
- 中文名称：
- Bovine prolactin soluble receptor
- 英文名称：
- Bovine prolactin soluble receptor
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60571
- 规格：
- INQUIRE
- 保存建议：
- Lyophilized PRLR-ECD although stable at room temperature for 1-2 weeks, should be stored desiccated below -18 degree C or preferably even at -80 degree C to prevent dimer formation. Upon reconstitution PRLR-ECD should be stored sterile at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage at 4 degree C it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles as they cause oligomerization of the protein.
- 货期：
- 6-8周
- 纯度：
- Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
(c) Gel filtration at pH 8 under non denaturative conditions.
- 产品形式：
- Filtered White lyophilized (freeze-dried) powder.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. PRL receptor, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function. Recombinant bovine Prolactin Receptor Extra Cellular Domain (bPRLR-ECD) produced in E.Coli is a non-glycosylated, polypeptide chain containing 211 amino acids and having a molecular mass of 24482 kDa was prepared according to Tchelet (1995) J. Endocrinology 144, 393-403 and tested according to Gertler et al. (1996) JBC 271; 24482-91.
