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Clickable-TAT Azide (49-57)
Clickable-TAT Azide (49-57)
- 中文名称：
- Clickable-TAT Azide (49-57)
- 英文名称：
- Clickable-TAT Azide (49-57)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60589
- 规格：
- 1 mg|5 mg|2x5 mg|3x5 mg|4x5 mg
- 保存建议：
- Please store dry and frozen (-20°C). The undissolved peptide is stable below -20°C in the dark for long term storage. The solution stability has not been tested, therefore, prompt use is recormnended.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Dry
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
TFA salt 5-azido-pentanoyl-RKKRRQRRR-NH2 C58H114N34O14 MW: 1511.77 HIV TAT sequence 49-57 This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. TAT (49-57) is modified with 5-Azido-pentanoic acid for click chemistry. The azido group can react with alkyne containing molecules in the presence of Cu/CuSO4 yielding a conjugate crosslinked by a triazole moiety. The reaction can be applied for the conjugation of TAT to various molecules include oligonucleotides to facilitate cell penetration for therapeutic applications. S. Brown and D. Graham, Tet Lett, 51, 5032 (2010).
