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Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
- 中文名称：
- Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
- 英文名称：
- Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA62071
- 规格：
- INQUIRE
- 保存建议：
- Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Introduction: GPR119, expressed in the pancreas and gastrointestinal tract, encodes a member of the rhodopsin subfamily of Gprotein-coupled receptors. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.
Description: Human GPR119 ACTOne is a HEK293-CNG cell line that expresses recombinant human GPR119. HEK293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization which can be easily measured with fluorescent Membrane Potential Dye (Cat# MBS430187). The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR, or a fluorescence microplate reader.
