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gp120 (MN) (HIV-1/Clade B) (aa 30-513)
gp120 (MN) (HIV-1/Clade B) (aa 30-513)
- 中文名称：
- gp120 (MN) (HIV-1/Clade B) (aa 30-513)
- 英文名称：
- gp120 (MN) (HIV-1/Clade B) (aa 30-513)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA62181
- 规格：
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议：
- Store at -20°C. Stable for 6-months from the date of shipment when kept at 4°C. Non-hazardous. No MSDS required.
- 货期：
- 6-8周
- 纯度：
- > 95% purity (SDS-PAGE)
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: gp120 protein expressed and purified from 293 cell culture.
Introduction: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120. Gp120 is essential for virus entry into cells as it plays a vital role in attachment to specific cell surface receptors. These receptors are DC-SIGN, Heparan Sulfate Proteoglycan and a specific interaction with the CD4 receptor, particularly on helper T-cells. Binding to CD4 induces the start of a cascade of conformational changes in gp120 and gp41 that lead to the fusion of the viral with the host cell membrane. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.
